Facilities
Tiofarma operates three manufacturing facilities in Oud-Beijerland, the Netherlands, and holds both EU-GMP and FDA licenses.

At Tiofarma, we pride ourselves on our state-of-the-art facilities that support our comprehensive manufacturing and development capabilities. Our primary manufacturing facility is located in Oud-Beijerland, the Netherlands, and holds both EU-GMP and FDA licenses, ensuring the highest standards of quality and compliance.

Manufacturing facility
Our manufacturing facility in Oud-Beijerland is equipped to handle large-scale production of both nasal sprays and semi-solid formulations, including non-sterile creams, ointments, pastes, and liquids.
Nasal Spray production
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Comprehensive solutions for the development and large-scale manufacturing of uni-dose and bi-dose nasal sprays.
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State-of-the-art Grade D qualified manufacturing environment.
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Flexible batch sizes to meet varying demand, from small-batch clinical production to full-scale commercial manufacturing.
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Advanced quality assurance processes that comply with global regulatory standards, including EMA and FDA guidelines.
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Complete services including secondary packaging, blistering, and assembly of semi-finished products.
More about Nasal Spray production
Semi-Solid production
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Extensive capabilities for the commercial production of semi-solid formulations.
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Advanced technology and state-of-the-art equipment for high-volume production.
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Primary and secondary packaging solutions tailored to meet regulatory and commercial needs.
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Serialization services to ensure global compliance and traceability.
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Flexible production batch sizes to meet demand, from pilot batches to large-scale commercial production.
More about Semi-Solid production

R&D Facility
Complementing our manufacturing site is a modern, dedicated R&D facility featuring 400 m² of non-GMP clean rooms for formulation and process development. This facility is equipped with innovative R&D solutions and equipment.
Innovative R&D solutions:
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Expertise in pre-formulation and formulation development, process development and optimization, and clinical trial material production.
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Advanced analytical capabilities, including stability testing, process validation, and comprehensive analytical method development.
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Technology transfers and scale-up expertise to ensure efficient and accurate replication of production processes.
Laboratory and Pilot-Scale equipment:
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Equipment ranging from a few hundred milliliters to 60 liters, supporting a wide range of development activities.
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Advanced analytical laboratory outfitted with cutting-edge physicochemical equipment.
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